"The world is full of festival movies that never get out or go anywhere. If people are trying to break into Hollywood movies and bigger movies, not make something personal that they're going to put up on the Internet, they have to look at the commerciality of their subject matter and they have to fit what they're trying to say into a framework that is in some form entertaining for people. It has to be meaningful or moving or exciting or funny or dramatic. It can't just be what you'd tell your shrink, you know what I mean?
If they're trying to break into Hollywood, they have to be aware of something commercial in the project. Take a look at some of the things that have sold out of festivals. For example, Hustle & Flow. It's about a pimp. It's about sex. And money. That’s an easy sell."
Read the rest. It's an interesting read about someone who made it happen.